Missouri
Adult Use + MedicalSales LiveState Regulatory Profile · Medical est. 2018 · Adult use est. 2022
Legal Status
Adult Use + Medical
Medical since 2018
Adult use since 2022
Market Tier
Emerging
Maturity of the regulated market
Tax Rate
N/A
Cannabis excise / sales tax rate
Regulatory Framework
Program details
- Regulator
- DHSSSource
- Track & Trace
- METRC19 CSR 100-1.130 (Metrc)
- Lab Accreditation
- ISO 17025
- License Renewal
- Annual
- Application Fee
- $10,000
- Retail Cap
- No cap
- Apps Currently Open
- Yes
- Market Tier
- Emerging
Program Features
Permitted activities
- Adult-Use Delivery
- ✓ YES19 CSR 100-1.180 (Dispensary delivery)
- Consumption Sites
- ✗ NOMo. Const. art. XIV sec 2, 3(1)(i) (public use barred; no state lounge)
- Social Equity Program
- ✓ YESMo. Const. art. XIV sec 2 (microbusiness equity licenses)
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Regulatory Timeline
- JUN 2023REFORM
Automatic expungement deadline
Courts work toward Amendment 3’s mandate to automatically review and expunge eligible nonviolent cannabis convictions. More than 140,000 records are ultimately cleared — among the most comprehensive expungement provisions written directly into a legalization measure.
- FEB 3, 2023LEGALIZATION
Adult-use retail sales begin
Existing medical dispensaries begin adult-use sales just 87 days after the vote — one of the fastest voter-approval-to-retail transitions in the country. DHSS issued licenses a day earlier than its announced February 6 date.
- DEC 8, 2022LEGALIZATION
Possession legal; Amendment 3 takes effect
Adults 21+ may possess up to three ounces and home-cultivate with a registration card. Because legalization is enshrined in the state constitution, the legislature cannot amend or repeal it — only another voter amendment can.
- NOV 8, 2022LEGALIZATION
Voters approve Amendment 3
Missouri voters legalize adult-use cannabis 53% to 47% via constitutional amendment, also creating an equity-focused microbusiness license category and a 6% retail excise tax.
- OCT 2020PROCEDURAL
Medical cannabis sales begin
Missouri’s first licensed medical cannabis sales launch, building the dispensary and cultivation infrastructure later converted to adult-use.
- NOV 2018LEGALIZATION
Voters approve medical cannabis (Amendment 2)
Missouri voters approve Amendment 2 with about 66% support, establishing a constitutional medical cannabis program under the Department of Health and Senior Services.
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Regulatory profile data for Missouri is compiled from publicly available state sources and was last reviewed August 2026. Laws change frequently — verify with your state's official regulator before purchasing or consuming.